New Myzopodidae (Chiroptera) from the late Paleogene of Egypt: emended family diagnosis and biogeographic origins of Noctilionoidea.

Myzopodidae is a family of bats today represented by two extant species of the genus Myzopoda that are restricted to the island of Madagascar.These bats possess uniquely derived adhesive pads on their TV Remote thumbs and ankles that they use for clinging to smooth roosting surfaces.Only one fossil myzopodid has been reported previously, a humerus

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Mature Placenta with True Knot of the Umbilical Cord

Abstract This module contains a video presentation of the gross pathology of a true knot in the umbilical cord of a mature placenta.The surgical pathology grossing laboratory is a rich resource for teaching medical student about the gross appearance of many pathologic processes.Dissection of freshly removed surgical specimens can reveal gross patho

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Bone marrow MSC from pediatric patients with B-ALL highly immunosuppress T-cell responses but do not compromise CD19-CAR T-cell activity

Background Although adoptive transfer of CD19-directed chimeric antigen receptor (CAR) T-cells (CD19-CAR T-cells) achieves high rates of complete response in patients with B-cell acute lymphoblastic leukemia (B-ALL), relapse is common.Bone marrow (BM) mesenchymal stem/stromal cells (BM-MSC) are key components of the hematopoietic niche and Pipe Wel

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Treatment with MDL 72527 Ameliorated Clinical Symptoms, Retinal Ganglion Cell Loss, Optic Nerve Inflammation, and Improved Visual Acuity in an Experimental Model of Multiple Sclerosis

Multiple Sclerosis (MS) is a highly disabling neurological disease characterized by inflammation, neuronal damage, and demyelination.Vision impairment is one of the major clinical features of MS.Previous studies from our lab have shown that MDL 72527, a pharmacological inhibitor of spermine oxidase (SMOX), is protective against neurodegeneration an

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